This special issue of the journal “Neutrosophic Sets and Systems” compiles a selection of notable works from the IX Ibero-American Biometry Meeting, held in Quito, Ecuador. The collection focuses on the application of neutrosophic and plithogenic approaches to data science and multivariate analysis. The papers explore advanced studies in neutrosophy, which is a branch of philosophy examining the origin, nature, and scope of neutralities. Neutrosophic theory generalizes classic logic by introducing a degree of indeterminacy, alongside degrees of truth and falsity. The articles within this volume demonstrate the application of these concepts to diverse fields, including financial dynamics, psychological treatments, cryptocurrency regulation, sentiment analysis, and the evaluation of public policies.